science science

List of Publications

Original Articles, Reviews, Letters, Editorials, etc

PI’s full list with citations:
Wordcloud of titles: 🧠

Hitchings MDT, Huang AT, Ranzani OT, GarcĂ­a-Carreras B, Nogueira ML, Ko AI, Croda J, Salje H, Cummings DAT (2026). Immune-mediated protection and enhancement of dengue drives patterns of infant cases in Brazil. Nat Commun. 10.1038/s41467-026-69111-x.

De Morais Batista F, Carcamo PM, Nelson E, Ranzani OT, ..., Maymone Gonçalves CC, Croda J (2026). The impact of large-scale release of Wolbachia mosquitoes on dengue incidence in Campo Grande, Brazil: an ecological study. Lancet Reg Health Am. 54:101327. 10.1016/j.lana.2025.101327.

Ranzani OT, Lazar Neto F, Mareto LK, ..., Hitchings MDT, Croda J (2026). Effectiveness of the TAK-003 dengue vaccine in adolescents during the 2024 outbreak in SĂŁo Paulo, Brazil: a test-negative, case-control study. Lancet Infect Dis. 26(1):91-100. 10.1016/s1473-3099(25)00382-2.

Ranzani OT, Singer M, Salluh JIF, ..., Rhodes A, Moreno R (2025). Development and Validation of the Sequential Organ Failure Assessment (SOFA)-2 Score. JAMA. 334(23):2090-2103. 10.1001/jama.2025.20516.

Ranzani OT, Martín Pérez C, Rubio R, ..., Moncunill G, Dobaño C (2025). Primary SARS-CoV-2 exposure by vaccination or infection shapes immune responses to omicron variants among a Spanish cohort. Nat Commun. 17(1):863. 10.1038/s41467-025-67577-9.

Salluh JIF, Amado F, Pisani L, ..., Ferreira JC, Ranzani OT (2025). Critical care research in low- and middle-income countries: a narrative review. Thorax. 10.1136/thorax-2024-221988.

Kreling GAD, Ranzani OT, Besen BAMP (2025). Persistent Critical Illness Across Borders: Are We Ready to Identify Them?. Crit Care Med. 53(12):e2804-e2805. 10.1097/ccm.0000000000006868.

Maia IWA, Decker SRR, Oliveira J E Silva L, Ranzani OT, ..., Besen BAMP, Brazilian Airway Registry Cooperation (BARCO) Group (2025). Ketamine, Etomidate, and Mortality in Emergency Department Intubations. JAMA Netw Open. 8(12):e2548060. 10.1001/jamanetworkopen.2025.48060.

Reinikainen M, Delamarre L, Blaser AR, Ranzani OT, ..., Singer M, Lakbar I (2025). Association of noradrenaline dose with mortality in critically ill patients: a systematic review and dose-response meta-analysis. Crit Care. 29(1):498. 10.1186/s13054-025-05717-9.

Silveira IH, Rebouças P, Pescarini J, ..., Ranzani OT, Paixao ES (2025). Effects of ambient temperature on under-five mortality: a nationwide space-time-stratified case-crossover study in Brazil. Environ Res. 285(Pt 5):122683. 10.1016/j.envres.2025.122683.

Moralez GM, Ranzani OT, Quintairos A, Salluh JIF (2025). Understanding ICU Outcomes: Lessons From National ICU Registries. Crit Care Med. 53(11):e2338-e2342. 10.1097/ccm.0000000000006853.

Cortes TR, Pescarini JM, Ranzani OT, ..., Silveira IH, Barreto ML (2025). Ambient temperature and non-accidental mortality: A nationwide space-time-stratified case-crossover study within the 100 million Brazilian Cohort. Environ Int. 205:109892. 10.1016/j.envint.2025.109892.

Dorn De Carvalho JM, McGuire SS, Oliveira LLR, Ranzani OT, ..., Hajjar LA, Maia IWA (2025). Prevalence and Impact of Violence Against Healthcare Workers in Brazilian Emergency Departments: A National Survey. West J Emerg Med. 26(6):1769-1780. 10.5811/westjem.45138.

Moreno R, Rhodes A, Ranzani OT, ..., Shankar-Hari M, Singer M (2025). Rationale and Methodological Approach Underlying the Development of the Sequential Organ Failure Assessment (SOFA)-2 Score: A Consensus Statement. JAMA Netw Open. 8(10):e2545040. 10.1001/jamanetworkopen.2025.45040.

Ostermann M, Alshamsi F, Artigas Raventos A, Ranzani OT, ..., De Backer D, European Society of Intensive Care Medicine (2025). European Society of Intensive Care Medicine Clinical Practice Guideline on fluid therapy in adult critically ill patients: Part 3-fluid removal at de-escalation phase. Intensive Care Med. 51(10):1749-1763. 10.1007/s00134-025-08058-x.

Peres IT, Ranzani OT, Bastos LSL, Hamacher S, Edinburgh T, Garcia-Gallo E, Bozza FA (2025). Clinical characteristics, complications and outcomes of critically ill patients with Dengue in Brazil, 2012-2024: A nationwide, multicenter cohort study. Int J Infect Dis. 159:108023. 10.1016/j.ijid.2025.108023.

Forte DN, Ramos JGR, Ranzani OT (2025). Allostatic overload as the pathophysiological basis for integrating palliative care in the Intensive Care Unit. Intensive Care Med. 51(9):1717-1720. 10.1007/s00134-025-08054-1.

Rashan A, Püttmann DP, De Keizer NF, Ranzani OT, ..., Bakhshi-Raiez F, Collaboration for Research, Implementation and Training in Critical Care—Asia and Africa Investigators, and the Dutch National Intensive Care Registry (2025). Using the Observational Medical Outcomes Partnership Common Data Model for a multi-registry intensive care unit benchmarking federated analysis: lessons learned. JAMIA Open. 8(4):ooaf052. 10.1093/jamiaopen/ooaf052.

Spies CD, Ranzani OT (2025). Telemedicine in critical care. Intensive Care Med. 51(6):1153-1156. 10.1007/s00134-025-07955-5.

Reyes LF, Sanabria-Herrera N, Nseir S, Ranzani OT, ..., Martin-Loeches I, European Network for ICU-Related Respiratory Infections (ENIRRIs) European Respiratory Society-Clinical Research Collaboration Investigators (2025). Nosocomial lower respiratory tract infections in patients with immunosuppression: a cohort study. Ann Intensive Care. 15(1):61. 10.1186/s13613-025-01462-y.

Maia IWA, Besen BAMP, Silva LOJE, Ranzani OT, ..., Alencar JCG, BARCO Group (2025). Peri-intubation adverse events and clinical outcomes in emergency department patients: the BARCO study. Crit Care. 29(1):155. 10.1186/s13054-025-05392-w.

Maia IWA, Besen BAMP, Silva LOJE, Ranzani OT, ..., Alencar JCG, BARCO Group (2025). Peri-intubation adverse events and clinical outcomes in emergency department patients: the BARCO study. Crit Care. 29(1):155. 10.1186/s13054-025-05392-w.

Martin FP, Poulain C, Mulier JH, Ranzani OT, ..., Cremer O, Roquilly A (2025). Identification and validation of robust hospital-acquired pneumonia subphenotypes associated with all-cause mortality: a multi-cohort derivation and validation. Intensive Care Med. 51(4):692-707. 10.1007/s00134-025-07884-3.

Borges IC, Lino FM, Luna-Muschi A, ..., Costa SF, Ranzani OT (2025). TB as a risk factor for severe COVID-19 mortality. Int J Tuberc Lung Dis. 29(4):186-188. 10.5588/ijtld.24.0503.

Mekontso Dessap A, Alshamsi F, Belletti A, ..., Alhazzani W, European Society of Intensive Care Medicine (2025). European Society of Intensive Care Medicine (ESICM) 2025 clinical practice guideline on fluid therapy in adult critically ill patients: part 2-the volume of resuscitation fluids. Intensive Care Med. 51(3):461-477. 10.1007/s00134-025-07840-1.

Wagstaff D, Amuasi J, Arfin S, Ranzani OT, ..., Waweru-Siika W, Beane A (2025). Evidence based QUality Improvement for Prescribing Stewardship in ICU (EQUIPS-ICU): protocol for type III hybrid implementation-effectiveness study. Implement Sci. 20(1):12. 10.1186/s13012-024-01413-4.

Lopes R, Basagaña X, Bastos LSL, Bozza FA, Ranzani OT (2025). Ambient temperature and dengue hospitalization in Brazil: A 10-year period case time series analysis. Environ Epidemiol. 9(1):e360. 10.1097/ee9.0000000000000360.

Reyes LF, Torres A, Olivella-Gomez J, Ranzani OT, ..., Martin-Loeches I, European Network for ICU-Related Respiratory Infections (ENIRRIs) European Respiratory Society-Clinical Research Collaboration Investigators (2025). Factors Associated with Mortality in Nosocomial Lower Respiratory Tract Infections: An ENIRRI Analysis. Antibiotics (Basel). 14(2). 10.3390/antibiotics14020127.

Vieceli T, Croda J, Bastos LSL, Bozza FA, Ranzani OT (2025). The burden, clinical features and outcomes of SARS-CoV-2, Influenza and co-infections during concurrently out-of-season outbreaks in Brazil. Public Health. 238:101-107. 10.1016/j.puhe.2024.10.016.

Cola JP, Do Prado TN, Ranzani OT, ..., Noia Maciel EL, Vicente CR (2025). Sociodemographic characteristics, clinical manifestations, and concurrent outcomes of Oropouche fever and dengue in EspĂ­rito Santo, Brazil. Rev Panam Salud Publica. 49:e127. 10.26633/rpsp.2025.127.

Pepper M, Rebouças P, Falcão IR, Ranzani OT, ..., Barreto ML, Paixao ES (2025). Prenatal exposure to ambient air pollution and subsequent risk of lower respiratory tract infections in childhood and adolescence: A systematic review. Int J Hyg Environ Health. 263:114473. 10.1016/j.ijheh.2024.114473.

Alari A, Ranzani OT, Milà C, Olmos S, Basagaña X, Dadvand P, Duarte-Salles T, Nieuwenhuijsen M, Tonne C (2025). Long-term exposure to air pollution and lower respiratory infections in a large population-based adult cohort in Catalonia. Environ Int. 195:109230. 10.1016/j.envint.2024.109230.

Besen BAMP, Nassar AP Jr, Ferreira JC, Ranzani OT (2025). Common pitfalls in critical care research. Crit Care Sci. 37:e20250339. 10.62675/2965-2774.20250339.

Pereira AJ, Noritomi DT, Dos Santos MC, ..., Serpa Neto A, Ranzani OT (2024). Effect of Tele-ICU on Clinical Outcomes of Critically Ill Patients: The TELESCOPE Randomized Clinical Trial. JAMA. 332(21):1798-1807. 10.1001/jama.2024.20651.

Ranzani OT, Annane D, Singer M (2024). Fludrocortisone with hydrocortisone in sepsis: new evidence in an ongoing debate. Intensive Care Med. 50(12):2138-2140. 10.1007/s00134-024-07699-8.

Reyes LF, Serrano-Mayorga CC, Zhang Z, Ranzani OT, ..., Conway Morris A, D-PRISM Investigators (2024). D-PRISM: a global survey-based study to assess diagnostic and treatment approaches in pneumonia managed in intensive care. Crit Care. 28(1):381. 10.1186/s13054-024-05180-y.

Saucy A, Espinosa A, Iraola-Guzmán S, Castaño-Vinyals G, Harding BN, Karachaliou M, Ranzani OT, De Cid R, Garcia-Aymerich J, Kogevinas M (2024). Environmental Exposures and Long COVID in a Prospective Population-Based Study in Catalonia (COVICAT Study). Environ Health Perspect. 132(11):117701. 10.1289/ehp15377.

Azambuja P, Bastos LSL, Batista-Da-Silva AA, Ranzani OT, ..., Hamacher S, Bozza FA (2024). Prevalence, risk factors, and impact of long COVID in a socially vulnerable community in Brazil: a prospective cohort study. Lancet Reg Health Am. 37:100839. 10.1016/j.lana.2024.100839.

Karachaliou M, Ranzani OT, Espinosa A, ..., Moncunill G, Kogevinas M (2024). Antibody responses to common viruses according to COVID-19 severity and postacute sequelae of COVID-19. J Med Virol. 96(9):e29862. 10.1002/jmv.29862.

Amin AB, Hitchings MDT, Ranzani OT, Andrews JR, Cummings DAT, Ko AI, Croda J, Dean NE (2024). Severity-dependent test-seeking behaviors and test-negative designs: impact on estimated vaccine effectiveness and utility of analytic and design choices. Am J Epidemiol. 194(7):1855-62. 10.1093/aje/kwae303.

Lazar Neto F, Ceccato A, Ranzani OT (2024). Vaccination against COVID-19 in a post-pandemic era. COVID-19: An Update (ERS Monograph). 2024. pp. 79–103. 10.1183/2312508X.10020223.

Batista-Da-Silva AA, Bastos LSL, Arouca LE, Gonzaga-Da-Silva TW, Hamacher S, Bozza FA, Ranzani OT (2024). #VacinaMare campaign: addressing vaccine inequity in socially vulnerabilised communities. Lancet Reg Health Am. 36:100827. 10.1016/j.lana.2024.100827.

Aguilar S, Bastos LSL, Maçaira P, Baião F, Simões P, Cerbino-Neto J, Ranzani OT, Hamacher S, Bozza FA (2024). Impact of the first year of COVID-19 vaccination strategy in Brazil: an ecological study. BMJ Open. 14(7):e072314. 10.1136/bmjopen-2023-072314.

Lazar Neto F, Mercadé-Besora N, Raventós B, Pérez-Crespo L, Castro Junior G, Ranzani OT, Duarte-Salles T (2024). Effectiveness of COVID-19 vaccines against severe COVID-19 among patients with cancer in Catalonia, Spain. Nat Commun. 15(1):5088. 10.1038/s41467-024-49285-y.

Lazar Neto F, Hitchings MDT, Amin AB, ..., Croda J, Ranzani OT (2024). Effectiveness of the fourth dose of COVID-19 vaccines against severe COVID-19 among adults 40 years or older in Brazil: a population-based cohort study. Lancet Reg Health Am. 34:100755. 10.1016/j.lana.2024.100755.

Bastos LSL, Hamacher S, Kurtz P, Ranzani OT, Zampieri FG, Soares M, Bozza FA, Salluh JIF (2024). The Association Between Prepandemic ICU Performance and Mortality Variation in COVID-19: A Multicenter Cohort Study of 35,619 Critically Ill Patients. Chest. 165(4):870-880. 10.1016/j.chest.2023.10.011.

Ranzani OT, Alari A, Olmos S, ..., Vivanco-Hidalgo RM, Tonne C (2024). Who is more vulnerable to effects of long-term exposure to air pollution on COVID-19 hospitalisation?. Environ Int. 185:108530. 10.1016/j.envint.2024.108530.

Alari A, Ranzani OT, Olmos S, ..., Vivanco-Hidalgo RM, Tonne C (2024). Short-term exposure to air pollution and hospital admission after COVID-19 in Catalonia: the COVAIR-CAT study. Int J Epidemiol. 53(2). 10.1093/ije/dyae041.

Laporte LR, Chavez AVFG, Ranzani OT, Caldas J, Passos RDH, Ramos JGR (2024). Long-term outcomes for epidemic viral pneumonia survivors after discharge from the intensive care unit: a systematic review. Einstein (Sao Paulo). 22(spe1):eRW0352. 10.31744/einstein_journal/2024rw0352.

Dumas G, Arabi YM, Bartz R, Ranzani OT, Scheibe F, Darmon M, Helms J (2024). Diagnosis and management of autoimmune diseases in the ICU. Intensive Care Med. 50(1):17-35. 10.1007/s00134-023-07266-7.

Salluh JIF, Besen BAMP, González-Dambrauskas S, Ranzani OT, ..., Ferreira JC, Nassar Junior AP (2024). Closing the critical care knowledge gap: the importance of publications from low-income and middle-income countries. Crit Care Sci. 36:e20240251eden. 10.62675/2965-2774.20240251ed-en.

Strumann C, Ranzani OT, Moor J, Berner R, Töpfner N, Chao CM, Moor MB (2023). Effectiveness of the BNT162b2 mRNA COVID-19 vaccine in children under 5 years. J Clin Invest. 133(21). 10.1172/jci173329.

Martin-Loeches I, Reyes LF, Nseir S, Ranzani OT, ..., Torres A, European Network for ICU-Related Respiratory Infections (ENIRRIs) European Respiratory Society-Clinical Research Collaboration Investigators (2023). European Network for ICU-Related Respiratory Infections (ENIRRIs): a multinational, prospective, cohort study of nosocomial LRTI. Intensive Care Med. 49(10):1212-1222. 10.1007/s00134-023-07210-9.

Parotto M, Gyöngyösi M, Howe K, Myatra SN, Ranzani OT, Shankar-Hari M, Herridge MS (2023). Post-acute sequelae of COVID-19: understanding and addressing the burden of multisystem manifestations. Lancet Respir Med. 11(8):739-754. 10.1016/s2213-2600(23)00239-4.

Pescarini JM, Cardoso AM, Santos RV, Ranzani OT, ..., Barreto ML, Barral-Netto M (2023). Vaccine coverage and effectiveness against laboratory-confirmed symptomatic and severe Covid-19 in indigenous people in Brazil: a cohort study. BMC Public Health. 23(1):1267. 10.1186/s12889-023-16196-4.

DP-EFFECT-BRAZIL Investigators (2023). Variants of concern and clinical outcomes in critically ill COVID-19 patients. Intensive Care Med. 49(6):697-699. 10.1007/s00134-023-07039-2.

Ranzani OT, Alari A, Olmos S, ..., Vivanco R, Tonne C (2023). Long-term exposure to air pollution and severe COVID-19 in Catalonia: a population-based cohort study. Nat Commun. 14(1):2916. 10.1038/s41467-023-38469-7.

Batista-Da-Silva AA, Moraes CB, Bozza HR, Bastos LDSL, Ranzani OT, Hamacher S, Bozza FA, ComitĂŞ Gestor ConexĂŁo SaĂşde (2023). Effectiveness of a multicomponent intervention to face the COVID-19 pandemic in Rio de Janeiro's favelas: difference-in-differences analysis. BMJ Glob Health. 8(5). 10.1136/bmjgh-2022-009997.

Pinar-Martí A, Gignac F, Fernández-Barrés S, Ranzani OT, ..., Sunyer J, Julvez J (2023). Effect of walnut consumption on neuropsychological development in healthy adolescents: a multi-school randomised controlled trial. EClinicalMedicine. 59:101954. 10.1016/j.eclinm.2023.101954.

Hastenreiter Filho HN, Peres IT, Maddalena LG, Baião FA, Ranzani OT, Hamacher S, Maçaira PM, Bozza FA (2023). What we talk about when we talk about COVID-19 vaccination campaign impact: a narrative review. Front Public Health. 11:1126461. 10.3389/fpubh.2023.1126461.

Besen BAMP, Ranzani OT, Singer M (2023). Management of diabetic ketoacidosis. Intensive Care Med. 49(1):95-98. 10.1007/s00134-022-06894-9.

Battaini LC, Ranzani OT, Marçal LJ, Antonangelo L, Jorge LB, Bitencourt CD, Woronik V, Malheiros DMA, Yu L (2022). Determination of Anti-Phospholipase A2 and Anti-Thrombospondin Type 1 Domain-Containing Protein 7A in Latin Patients with Membranous Nephropathy. Diagnostics (Basel). 13(1). 10.3390/diagnostics13010017.

Lind ML, Robertson AJ, Silva J, Ranzani OT, ..., Hitchings MDT, Schulz WL (2022). Association between primary or booster COVID-19 mRNA vaccination and Omicron lineage BA.1 SARS-CoV-2 infection in people with a prior SARS-CoV-2 infection: A test-negative case-control analysis. PLoS Med. 19(12):e1004136. 10.1371/journal.pmed.1004136.

Ranzani OT, Hitchings MDT, De Melo RL, ..., Ko AI, Croda J (2022). Effectiveness of an inactivated Covid-19 vaccine with homologous and heterologous boosters against Omicron in Brazil. Nat Commun. 13(1):5536. 10.1038/s41467-022-33169-0.

Rasella D, Ranzani OT (2022). The importance for tuberculosis of mitigating economic crises. Lancet Glob Health. 10(10):e1371-e1372. 10.1016/s2214-109x(22)00366-7.

Bastos LSL, Aguilar S, Rache B, Maçaira P, Baião F, Cerbino-Neto J, Rocha R, Hamacher S, Ranzani OT, Bozza FA (2022). Primary healthcare protects vulnerable populations from inequity in COVID-19 vaccination: An ecological analysis of nationwide data from Brazil. Lancet Reg Health Am. 14:100335. 10.1016/j.lana.2022.100335.

Dhanani J, Taniguchi LU, Ranzani OT (2022). Optimising aerosolized therapies in critically ill patients. Intensive Care Med. 48(10):1418-1421. 10.1007/s00134-022-06800-3.

Nassar AP Jr, Archanjo LVF, Ranzani OT, ..., Caruso P, Soares M (2022). Characteristics and outcomes of autologous hematopoietic stem cell transplant recipients admitted to intensive care units: A multicenter study. J Crit Care. 71:154077. 10.1016/j.jcrc.2022.154077.

Ranzani OT, Niederman MS, Torres A (2022). Ventilator-associated pneumonia. Intensive Care Med. 48(9):1222-1226. 10.1007/s00134-022-06773-3.

Ranzani OT, Bozza FA (2022). Vaccine effectiveness of ChAdOx1 nCoV-19 against COVID-19 in a socially vulnerable community in Rio de Janeiro, Brazil: author's response. Clin Microbiol Infect. 28(8):1166-1167. 10.1016/j.cmi.2022.03.037.

Ranzani OT, Kalra A, Di Girolamo C, Curto A, Valerio F, Halonen JI, Basagaña X, Tonne C (2022). Urban-rural differences in hypertension prevalence in low-income and middle-income countries, 1990-2020: A systematic review and meta-analysis. PLoS Med. 19(8):e1004079. 10.1371/journal.pmed.1004079.

Fernando SM, Ranzani OT, Herridge MS (2022). Mental health morbidity, self-harm, and suicide in ICU survivors and caregivers. Intensive Care Med. 48(8):1084-1087. 10.1007/s00134-022-06743-9.

Halpern B, Ranzani OT (2022). Lessons From the COVID-19 Pandemic in Latin America: Vulnerability Leading to More Vulnerability. Am J Public Health. 112(S6):S579-S580. 10.2105/ajph.2022.306812.

Hitchings MDT, Lewnard JA, Dean NE, Ko AI, Ranzani OT, Andrews JR, Cummings DAT (2022). Use of Recently Vaccinated Individuals to Detect Bias in Test-Negative Case-Control Studies of COVID-19 Vaccine Effectiveness. Epidemiology. 33(4):450-456. 10.1097/ede.0000000000001484.

Møller MH, Alhazzani W, Lewis K, Ranzani OT, ..., Pandharipande P, Ostermann M (2022). Use of dexmedetomidine for sedation in mechanically ventilated adult ICU patients: a rapid practice guideline. Intensive Care Med. 48(7):801-810. 10.1007/s00134-022-06660-x.

Brizzi A, Whittaker C, Servo LMS, Ranzani OT, ..., Bhatt S, Ratmann O (2022). Spatial and temporal fluctuations in COVID-19 fatality rates in Brazilian hospitals. Nat Med. 28(7):1476-1485. 10.1038/s41591-022-01807-1.

Ranzani OT, Bhogadi S, MilĂ  C, Kulkarni B, Balakrishnan K, Sambandam S, Garcia-Aymerich J, Marshall JD, Kinra S, Tonne C (2022). Association of ambient and household air pollution with lung function in young adults in an peri-urban area of South-India: A cross-sectional study. Environ Int. 165:107290. 10.1016/j.envint.2022.107290.

Hitchings MDT, Ranzani OT, Lind ML, ..., Ko AI, Croda J (2022). Change in covid-19 risk over time following vaccination with CoronaVac: test negative case-control study. BMJ. 377:e070102. 10.1136/bmj-2022-070102.

De Macedo Couto R, Santana GO, Ranzani OT, Waldman EA (2022). One Health and surveillance of zoonotic tuberculosis in selected low-income, middle-income and high-income countries: A systematic review. PLoS Negl Trop Dis. 16(6):e0010428. 10.1371/journal.pntd.0010428.

Cerqueira-Silva T, Andrews JR, Boaventura VS, Ranzani OT, ..., Croda J, Barral-Netto M (2022). Effectiveness of CoronaVac, ChAdOx1 nCoV-19, BNT162b2, and Ad26.COV2.S among individuals with previous SARS-CoV-2 infection in Brazil: a test-negative, case-control study. Lancet Infect Dis. 22(6):791-801. 10.1016/s1473-3099(22)00140-2.

Ranzani OT, Silva AAB, Peres IT, Antunes BBP, Gonzaga-Da-Silva TW, Soranz DR, Cerbino-Neto J, Hamacher S, Bozza FA (2022). Vaccine effectiveness of ChAdOx1 nCoV-19 against COVID-19 in a socially vulnerable community in Rio de Janeiro, Brazil: a test-negative design study. Clin Microbiol Infect. 28(5):736.e1-736.e4. 10.1016/j.cmi.2022.01.032.

Pereira SM, Sinedino BE, Costa ELV, Ranzani OT, ..., Brochard L, Amato MBP (2022). Phrenic Nerve Block and Respiratory Effort in Pigs and Critically Ill Patients with Acute Lung Injury. Anesthesiology. 136(5):763-778. 10.1097/aln.0000000000004161.

Ceccato A, Dominedò C, Ferrer M, Ranzani OT, ..., Antonelli M, Torres A (2022). Prediction of ventilator-associated pneumonia outcomes according to the early microbiological response: a retrospective observational study. Eur Respir J. 59(4). 10.1183/13993003.00620-2021.

Croda J, Ranzani OT (2022). Booster doses for inactivated COVID-19 vaccines: if, when, and for whom. Lancet Infect Dis. 22(4):430-432. 10.1016/s1473-3099(21)00696-4.

Ranzani OT, Pereira AJ, Santos MCD, ..., Serpa Neto A, Noritomi DT (2022). Statistical analysis of a cluster-randomized clinical trial on adult general intensive care units in Brazil: TELE-critical care verSus usual Care On ICU PErformance (TELESCOPE) trial. Rev Bras Ter Intensiva. 34(1):87-95. 10.5935/0103-507x.20220003-pt.

Cerbino-Neto J, Peres IT, Varela MC, Ranzani OT, ..., Bozza FA, Penna GO (2022). Seroepidemiology of SARS-CoV-2 on a partially vaccinated island in Brazil: Determinants of infection and vaccine response. Front Public Health. 10:1017337. 10.3389/fpubh.2022.1017337.

Brizzi A, Whittaker C, Servo LMS, Ranzani OT, ..., Bhatt S, Ratmann O (2021). Report 46: Factors driving extensive spatial and temporal fluctuations in COVID-19 fatality rates in Brazilian hospitals. medRxiv. 10.1101/2021.11.01.21265731.

Hitchings MDT, Ranzani OT, Dorion M, ..., Ko AI, Croda J (2021). Effectiveness of ChAdOx1 vaccine in older adults during SARS-CoV-2 Gamma variant circulation in SĂŁo Paulo. Nat Commun. 12(1):6220. 10.1038/s41467-021-26459-6.

Hitchings MDT, Ranzani OT, Torres MSS, ..., Ko AI, Croda J (2021). Effectiveness of CoronaVac among healthcare workers in the setting of high SARS-CoV-2 Gamma variant transmission in Manaus, Brazil: A test-negative case-control study. Lancet Reg Health Am. 1:100025. 10.1016/j.lana.2021.100025.

Ranzani OT, Hitchings MDT, Dorion M, ..., Ko AI, Croda J (2021). Effectiveness of the CoronaVac vaccine in older adults during a gamma variant associated epidemic of covid-19 in Brazil: test negative case-control study. BMJ. 374:n2015. 10.1136/bmj.n2015.

Parotto M, Myatra SN, Munblit D, Elhazmi A, Ranzani OT, Herridge MS (2021). Recovery after prolonged ICU treatment in patients with COVID-19. Lancet Respir Med. 9(8):812-814. 10.1016/s2213-2600(21)00318-0.

Bastos LS, Ranzani OT, Souza TML, Hamacher S, Bozza FA (2021). COVID-19 hospital admissions: Brazil's first and second waves compared. Lancet Respir Med. 9(8):e82-e83. 10.1016/s2213-2600(21)00287-3.

Lazar Neto F, Marino LO, Torres A, Ranzani OT, ..., Residents, Attending Physicians (2021). Community-acquired pneumonia severity assessment tools in patients hospitalized with COVID-19: a validation and clinical applicability study. Clin Microbiol Infect. 27(7):1037.e1-1037.e8. 10.1016/j.cmi.2021.03.002.

Martin-Loeches I, Ceccato A, Carbonara M, Ranzani OT, ..., Ferrer M, Torres A (2021). Impact of Cardiovascular Failure in Intensive CareUnit-Acquired Pneumonia: A Single-Center, Prospective Study. Antibiotics (Basel). 10(7). 10.3390/antibiotics10070798.

Noritomi DT, Ranzani OT, Ferraz LJR, ..., Pereira AJ, TELESCOPE Trial Investigators (2021). TELE-critical Care verSus usual Care On ICU PErformance (TELESCOPE): protocol for a cluster-randomised clinical trial on adult general ICUs in Brazil. BMJ Open. 11(6):e042302. 10.1136/bmjopen-2020-042302.

Ramos JGR, Ranzani OT, Dias RD, Forte DN (2021). Impact of nonclinical factors on intensive care unit admission decisions: a vignette-based randomized trial (V-TRIAGE). Rev Bras Ter Intensiva. 33(2):219-230. 10.5935/0103-507x.20210029.

Ranzani OT, Bastos LSL, Gelli JGM, Marchesi JF, BaiĂŁo F, Hamacher S, Bozza FA (2021). Characterisation of the first 250,000 hospital admissions for COVID-19 in Brazil: a retrospective analysis of nationwide data. Lancet Respir Med. 9(4):407-418. 10.1016/s2213-2600(20)30560-9.

Ranzani OT, Pescarini JM, Martinez L, Garcia-Basteiro AL (2021). Increasing tuberculosis burden in Latin America: an alarming trend for global control efforts. BMJ Glob Health. 6(3). 10.1136/bmjgh-2021-005639.

Burn E, Sena AG, Prats-Uribe A, Ranzani OT, ..., Kostka K, Duarte-Salles T (2021). Use of dialysis, tracheostomy, and extracorporeal membrane oxygenation among 842,928 patients hospitalized with COVID-19 in the United States. medRxiv. 10.1101/2020.11.25.20229088.

Ceccato A, Mendez R, Ewig S, Ranzani OT, ..., Menendez R, Torres A (2021). Validation of a Prediction Score for Drug-Resistant Microorganisms in Community-acquired Pneumonia. Ann Am Thorac Soc. 18(2):257-265. 10.1513/annalsats.202005-558oc.

Julvez J, Gignac F, Fernández-Barrés S, Ranzani OT, ..., Salas-Salvadó J, Sunyer J (2021). Walnuts, Long-Chain Polyunsaturated Fatty Acids, and Adolescent Brain Development: Protocol for the Walnuts Smart Snack Dietary Intervention Trial. Front Pediatr. 9:593847. 10.3389/fped.2021.593847.

Besen BAMP, Park M, Ranzani OT (2021). Noninvasive ventilation in critically ill very old patients with pneumonia: A multicenter retrospective cohort study. PLoS One. 16(1):e0246072. 10.1371/journal.pone.0246072.

Tonne C, Adair L, Adlakha D, Ranzani OT, ..., Van Wee B, Adli M (2021). Defining pathways to healthy sustainable urban development. Environ Int. 146:106236. 10.1016/j.envint.2020.106236.

Dimitrova A, Ingole V, Basagaña X, Ranzani OT, Milà C, Ballester J, Tonne C (2021). Association between ambient temperature and heat waves with mortality in South Asia: Systematic review and meta-analysis. Environ Int. 146:106170. 10.1016/j.envint.2020.106170.

Luyt CE, Bouadma L, Morris AC, Ranzani OT, ..., Torres A, Timsit JF (2020). Pulmonary infections complicating ARDS. Intensive Care Med. 46(12):2168-2183. 10.1007/s00134-020-06292-z.

Ranzani OT, Motos A, Chiurazzi C, Ceccato A, Rinaudo M, Li Bassi G, Ferrer M, Torres A (2020). Diagnostic accuracy of Gram staining when predicting staphylococcal hospital-acquired pneumonia and ventilator-associated pneumonia: a systematic review and meta-analysis. Clin Microbiol Infect. 26(11):1456-1463. 10.1016/j.cmi.2020.08.015.

Esperatti M, Fuentes N, Ferrer M, Ranzani OT, Li Bassi G, Singer M, Gonzalez ME, Peraita G, Urbano MS, Torres A (2020). Association between sepsis at ICU admission and mortality in patients with ICU-acquired pneumonia: An infectious second-hit model. J Crit Care. 59:207-214. 10.1016/j.jcrc.2020.06.012.

Vert C, Gascon M, Ranzani OT, ..., Elliott LR, Nieuwenhuijsen M (2020). Physical and mental health effects of repeated short walks in a blue space environment: A randomised crossover study. Environ Res. 188:109812. 10.1016/j.envres.2020.109812.

Einav S, Ranzani OT (2020). Focus on better care and ethics: Are medical ethics lagging behind the development of new medical technologies?. Intensive Care Med. 46(8):1611-1613. 10.1007/s00134-020-06112-4.

Ranzani OT, Monteiro MB, Besen BAMP, Azevedo LCP (2020). Association of Sepsis Diagnosis at Daytime and on Weekdays with Compliance with the 3-Hour Sepsis Treatment Bundles. A Multicenter Cohort Study. Ann Am Thorac Soc. 17(8):980-987. 10.1513/annalsats.201910-781oc.

Antunes BBP, Peres IT, BaiĂŁo FA, Ranzani OT, ..., Hamacher S, Bozza FA (2020). Progression of confirmed COVID-19 cases after the implementation of control measures. Rev Bras Ter Intensiva. 32(2):213-223. 10.5935/0103-507x.20200028.

Ranzani OT, MilĂ  C, Sanchez M, ..., Kinra S, Tonne C (2020). Personal exposure to particulate air pollution and vascular damage in peri-urban South India. Environ Int. 139:105734. 10.1016/j.envint.2020.105734.

Fernando SM, Tran A, Cheng W, Ranzani OT, ..., Guyatt GH, Rochwerg B (2020). Diagnosis of ventilator-associated pneumonia in critically ill adult patients-a systematic review and meta-analysis. Intensive Care Med. 46(6):1170-1179. 10.1007/s00134-020-06036-z.

Ranzani OT, Besen BAMP, Herridge MS (2020). Focus on the frail and elderly: who should have a trial of ICU treatment?. Intensive Care Med. 46(5):1030-1032. 10.1007/s00134-020-05963-1.

Ranzani OT, Tonne C, Barreto ML (2020). Potential for Life Course Health Benefits From Improved Household Environments. JAMA Netw Open. 3(4):e202968. 10.1001/jamanetworkopen.2020.2968.

MilĂ  C, Ranzani OT, Sanchez M, AmbrĂłs A, Bhogadi S, Kinra S, Kogevinas M, Dadvand P, Tonne C (2020). Land-Use Change and Cardiometabolic Risk Factors in an Urbanizing Area of South India: A Population-Based Cohort Study. Environ Health Perspect. 128(4):47003. 10.1289/ehp5445.

Vane MF, Pereira SM, Nassar AP Junior, Ranzani OT, Caruso P (2020). Selected oncological patients may even restart cancer treatment after in-hospital cardiac arrest. Resuscitation. 148:118-120. 10.1016/j.resuscitation.2019.12.041.

Ranzani OT, MilĂ  C, Sanchez M, ..., Kinra S, Tonne C (2020). Association between ambient and household air pollution with carotid intima-media thickness in peri-urban South India: CHAI-Project. Int J Epidemiol. 49(1):69-79. 10.1093/ije/dyz208.

Ranzani OT, MilĂ  C, Kulkarni B, Kinra S, Tonne C (2020). Association of Ambient and Household Air Pollution With Bone Mineral Content Among Adults in Peri-urban South India. JAMA Netw Open. 3(1):e1918504. 10.1001/jamanetworkopen.2019.18504.

Ranzani OT, Rodrigues LC, Bombarda S, Minto CM, Waldman EA, Carvalho CRR (2020). Long-term survival and cause-specific mortality of patients newly diagnosed with tuberculosis in SĂŁo Paulo state, Brazil, 2010-15: a population-based, longitudinal study. Lancet Infect Dis. 20(1):123-132. 10.1016/s1473-3099(19)30518-3.

Curto A, Ranzani OT, MilĂ  C, Sanchez M, Marshall JD, Kulkarni B, Bhogadi S, Kinra S, Wellenius GA, Tonne C (2019). Lack of association between particulate air pollution and blood glucose levels and diabetic status in peri-urban India. Environ Int. 131:105033. 10.1016/j.envint.2019.105033.

Ranzani OT, Coelho L, Torres A (2019). Biomarkers in community-acquired pneumonia: can we do better by using them correctly?. J Bras Pneumol. 45(4):e20190189. 10.1590/1806-3713/e20190189.

LĂłpez-Aguilar J, Bassi GL, QuĂ­lez ME, Ranzani OT, ..., Torres A, Blanch L (2019). Hippocampal Damage During Mechanical Ventilation in Trendelenburg Position: A Secondary Analysis of an Experimental Study on the Prevention of Ventilator-Associated Pneumonia. Shock. 52(1):75-82. 10.1097/shk.0000000000001237.

Curto A, Wellenius GA, MilĂ  C, Sanchez M, Ranzani OT, Marshall JD, Kulkarni B, Bhogadi S, Kinra S, Tonne C (2019). Ambient Particulate Air Pollution and Blood Pressure in Peri-urban India. Epidemiology. 30(4):492-500. 10.1097/ede.0000000000001014.

Ceccato A, Panagiotarakou M, Ranzani OT, ..., Bermejo-Martin JF, Torres A (2019). Lymphocytopenia as a Predictor of Mortality in Patients with ICU-Acquired Pneumonia. J Clin Med. 8(6). 10.3390/jcm8060843.

Li Bassi G, Motos A, Fernandez-Barat L, Ranzani OT, ..., Montgomery AB, Torres A (2019). Nebulized Amikacin and Fosfomycin for Severe Pseudomonas aeruginosa Pneumonia: An Experimental Study. Crit Care Med. 47(6):e470-e477. 10.1097/ccm.0000000000003724.

Ramos JGR, Ranzani OT, Perondi B, Dias RD, Jones D, Carvalho CRR, Velasco IT, Forte DN (2019). A decision-aid tool for ICU admission triage is associated with a reduction in potentially inappropriate intensive care unit admissions. J Crit Care. 51:77-83. 10.1016/j.jcrc.2019.02.002.

Ceccato A, Cilloniz C, Martin-Loeches I, Ranzani OT, Gabarrus A, Bueno L, Garcia-Vidal C, Ferrer M, Niederman MS, Torres A (2019). Effect of Combined β-Lactam/Macrolide Therapy on Mortality According to the Microbial Etiology and Inflammatory Status of Patients With Community-Acquired Pneumonia. Chest. 155(4):795-804. 10.1016/j.chest.2018.11.006.

Ranzani OT, Senussi T, Idone F, Ceccato A, Li Bassi G, Ferrer M, Torres A (2019). Invasive and non-invasive diagnostic approaches for microbiological diagnosis of hospital-acquired pneumonia. Crit Care. 23(1):51. 10.1186/s13054-019-2348-2.

Li Bassi G, Comaru T, MartĂ­ D, Ranzani OT, ..., Fraser J, Torres A (2019). Recruitment manoeuvres dislodge mucus towards the distal airways in an experimental model of severe pneumonia. Br J Anaesth. 122(2):269-276. 10.1016/j.bja.2018.07.039.

Macedo Couto R, Ranzani OT, Waldman EA (2019). Zoonotic Tuberculosis in Humans: Control, Surveillance, and the One Health Approach. Epidemiol Rev. 41(1):130-144. 10.1093/epirev/mxz002.

Ranzani OT, Shankar-Hari M, Harrison DA, Rabello LS, Salluh JIF, Rowan KM, Soares M (2019). A Comparison of Mortality From Sepsis in Brazil and England: The Impact of Heterogeneity in General and Sepsis-Specific Patient Characteristics. Crit Care Med. 47(1):76-84. 10.1097/ccm.0000000000003438.

Li Bassi G, Chiurazzi C, Aguilera E, Ranzani OT, ..., Chiumello D, Torres A (2018). In-vitro analysis of a novel 'add-on' silicone cuff to improve sealing properties of tracheal tubes. Anaesthesia. 73(11):1372-1381. 10.1111/anae.14413.

Li Bassi G, Prats RG, Artigas A, Ranzani OT, ..., Pelosi P, Torres A (2018). Appraisal of systemic inflammation and diagnostic markers in a porcine model of VAP: secondary analysis from a study on novel preventive strategies. Intensive Care Med Exp. 6(1):42. 10.1186/s40635-018-0206-1.

Tonne C, Ranzani OT (2018). Is occupational biomass smoke exposure an overlooked driver of respiratory health?. Occup Environ Med. 75(10):687-688. 10.1136/oemed-2017-104691.

Ranzani OT, De Pascale G, Park M (2018). Diagnosis of nonventilated hospital-acquired pneumonia: how much do we know?. Curr Opin Crit Care. 24(5):339-346. 10.1097/mcc.0000000000000525.

Ranzani OT, Taniguchi LU, Torres A (2018). Severity scoring systems for pneumonia: current understanding and next steps. Curr Opin Pulm Med. 24(3):227-236. 10.1097/mcp.0000000000000468.

Lange T, Skrifvars M, Ranzani OT (2018). Prompt admission to the ICU: an instrument to improve mortality for deteriorating ward patients. Intensive Care Med. 44(5):678-680. 10.1007/s00134-018-5194-9.

Ranzani OT, Rodrigues LC, Waldman EA, Prina E, Carvalho CRR (2018). Who are the patients with tuberculosis who are diagnosed in emergency facilities? An analysis of treatment outcomes in the state of SĂŁo Paulo, Brazil. J Bras Pneumol. 44(2):125-133. 10.1590/s1806-37562017000000384.

Ekren PK, Ranzani OT, Ceccato A, Li Bassi G, Muñoz Conejero E, Ferrer M, Niederman MS, Torres A (2018). Evaluation of the 2016 Infectious Diseases Society of America/American Thoracic Society Guideline Criteria for Risk of Multidrug-Resistant Pathogens in Patients with Hospital-acquired and Ventilator-associated Pneumonia in the ICU. Am J Respir Crit Care Med. 197(6):826-830. 10.1164/rccm.201708-1717le.

Moreau AS, Martin-Loeches I, Povoa P, ..., Nseir S, TAVeM Study Group (2018). Impact of immunosuppression on incidence, aetiology and outcome of ventilator-associated lower respiratory tract infections. Eur Respir J. 51(3). 10.1183/13993003.01656-2017.

Ranzani OT, Torres A, All Authors (2018). Reply to Akinosoglou and Gogos: Sepsis-3 in Community-acquired Pneumonia: How Reliable Is It?. Am J Respir Crit Care Med. 197(4):537-538. 10.1164/rccm.201708-1598le.

Dell'Aringa M, Ranzani OT, Bierens J, Murray V (2018). Rio's Mountainous Region ("RegiĂŁo Serrana") 2011 Landslides: Impact on Public Mental Health System. PLoS Curr. 10. 10.1371/currents.dis.156b98022b9421098142a4b31879d866.

Ferrer M, Travierso C, Cilloniz C, Gabarrus A, Ranzani OT, Polverino E, Liapikou A, Blasi F, Torres A (2018). Severe community-acquired pneumonia: Characteristics and prognostic factors in ventilated and non-ventilated patients. PLoS One. 13(1):e0191721. 10.1371/journal.pone.0191721.

Robert R, Skrifvars MB, Ranzani OT (2017). Is this critically ill patient elderly or too old?. Intensive Care Med. 43(12):1884-1886. 10.1007/s00134-017-4965-z.

Ranzani OT, Prina E, Menéndez R, ..., Ferrer M, Torres A (2017). New Sepsis Definition (Sepsis-3) and Community-acquired Pneumonia Mortality. A Validation and Clinical Decision-Making Study. Am J Respir Crit Care Med. 196(10):1287-1297. 10.1164/rccm.201611-2262oc.

Li Bassi G, Panigada M, Ranzani OT, ..., Torres A, Gravity-VAP Network (2017). Randomized, multicenter trial of lateral Trendelenburg versus semirecumbent body position for the prevention of ventilator-associated pneumonia. Intensive Care Med. 43(11):1572-1584. 10.1007/s00134-017-4858-1.

Zampieri FG, Soares M, Borges LP, Salluh JIF, Ranzani OT (2017). The Epimed Monitor ICU Database®: a cloud-based national registry for adult intensive care unit patients in Brazil. Rev Bras Ter Intensiva. 29(4):418-426. 10.5935/0103-507x.20170062.

De Pascale G, Ranzani OT, Nseir S, ..., Torres A, MartĂ­n-Loeches I (2017). Intensive care unit patients with lower respiratory tract nosocomial infections: the ENIRRIs project. ERJ Open Res. 3(4). 10.1183/23120541.00092-2017.

Fernández-Barat L, Motos A, Ranzani OT, ..., Antonelli M, Torres A (2017). Diagnostic Value of Endotracheal Aspirates Sonication on Ventilator-Associated Pneumonia Microbiologic Diagnosis. Microorganisms. 5(3). 10.3390/microorganisms5030062.

Martin-Loeches I, Zampieri F, Povoa P, Ranzani OT, Bos LD, Aliberti S, Torres A (2017). Respiratory research networks in Europe and beyond: aims, achievements and aspirations for the 21st century. Breathe (Sheff). 13(3):209-215. 10.1183/20734735.009217.

Darmon M, Ranzani OT, Azoulay E (2017). Focus on immunocompromised patients. Intensive Care Med. 43(9):1415-1417. 10.1007/s00134-017-4857-2.

Ceccato A, Ranzani OT, Torres A (2017). Rapid identification of antimicrobial resistance patterns allows a faster antibiotic adequacy. Crit Care. 21(1):208. 10.1186/s13054-017-1797-8.

Yamaguchi RS, Noritomi DT, Degaspare NV, Muñoz GOC, Porto APM, Costa SF, Ranzani OT (2017). Peripherally inserted central catheters are associated with lower risk of bloodstream infection compared with central venous catheters in paediatric intensive care patients: a propensity-adjusted analysis. Intensive Care Med. 43(8):1097-1104. 10.1007/s00134-017-4852-7.

Zampieri FG, Ranzani OT, Liborio AB, Kellum JA (2017). The authors reply. Crit Care Med. 45(2):e239-e240. 10.1097/ccm.0000000000002173.

Ceccato A, Cilloniz C, Ranzani OT, Menendez R, Agusti C, Gabarrus A, Ferrer M, Sibila O, Niederman MS, Torres A (2017). Treatment with macrolides and glucocorticosteroids in severe community-acquired pneumonia: A post-hoc exploratory analysis of a randomized controlled trial. PLoS One. 12(6):e0178022. 10.1371/journal.pone.0178022.

Ranzani OT, Rodrigues LC, Waldman EA, Carvalho CRR (2017). Estimating the impact of tuberculosis anatomical classification on treatment outcomes: A patient and surveillance perspective analysis. PLoS One. 12(11):e0187585. 10.1371/journal.pone.0187585.

Rosales-Mayor E, Polverino E, Raguer L, Alcaraz V, Gabarrus A, Ranzani OT, Menendez R, Torres A (2017). Comparison of two prognostic scores (BSI and FACED) in a Spanish cohort of adult patients with bronchiectasis and improvement of the FACED predictive capacity for exacerbations. PLoS One. 12(4):e0175171. 10.1371/journal.pone.0175171.

Ranzani OT, Li Bassi G, Torres A (2016). Prone position and VAP incidence in the PROSEVA trial: attention to the causal question when interpreting competing risk analysis. Intensive Care Med. 42(12):2119-2120. 10.1007/s00134-016-4469-2.

Torres A, Ranzani OT, Ferrer M (2016). Pneumonia in 2016: towards better care. Lancet Respir Med. 4(12):949-951. 10.1016/s2213-2600(16)30387-3.

Zampieri FG, Ranzani OT, Azevedo LC, Martins ID, Kellum JA, LibĂłrio AB (2016). Lactated Ringer Is Associated With Reduced Mortality and Less Acute Kidney Injury in Critically Ill Patients: A Retrospective Cohort Analysis. Crit Care Med. 44(12):2163-2170. 10.1097/ccm.0000000000001948.

Mendes ET, Ranzani OT, Marchi AP, Silva MTD, Filho JUA, Alves T, GuimarĂŁes T, Levin AS, Costa SF (2016). Chlorhexidine bathing for the prevention of colonization and infection with multidrug-resistant microorganisms in a hematopoietic stem cell transplantation unit over a 9-year period: Impact on chlorhexidine susceptibility. Medicine (Baltimore). 95(46):e5271. 10.1097/md.0000000000005271.

Ranzani OT, Simpson ES, JapiassĂş AM, Noritomi DT, Amil Critical Care Group (2016). The Challenge of Predicting Pressure Ulcers in Critically Ill Patients. A Multicenter Cohort Study. Ann Am Thorac Soc. 13(10):1775-1783. 10.1513/annalsats.201603-154oc.

Besen BA, Ranzani OT, Park M (2016). Timing of Initiation of Renal Replacement Therapy in Critically Ill Patients With Acute Kidney Injury. JAMA. 316(11):1213. 10.1001/jama.2016.11332.

El-Dash SA, Borges JB, Costa EL, Tucci MR, Ranzani OT, Caramez MP, Carvalho CR, Amato MB (2016). There is no cephalocaudal gradient of computed tomography densities or lung behavior in supine patients with acute respiratory distress syndrome. Acta Anaesthesiol Scand. 60(6):767-79. 10.1111/aas.12690.

Ranzani OT, Forte DN, Forte AC, Mimica I, Forte WC (2016). The value of antibody-coated bacteria in tracheal aspirates for the diagnosis of ventilator-associated pneumonia: a case-control study. J Bras Pneumol. 42(3):203-10. 10.1590/s1806-37562015000000244.

Ranzani OT, Carvalho CR, Waldman EA, Rodrigues LC (2016). The impact of being homeless on the unsuccessful outcome of treatment of pulmonary TB in SĂŁo Paulo State, Brazil. BMC Med. 14:41. 10.1186/s12916-016-0584-8.

Noritomi DT, Zigaib R, Ranzani OT, Teich V (2016). Evaluation of cost-effectiveness from the funding body's point of view of ultrasound-guided central venous catheter insertion compared with the conventional technique. Rev Bras Ter Intensiva. 28(1):62-9. 10.5935/0103-507x.20160014.

Nassar AP Jr, Zampieri FG, Ranzani OT, Park M (2015). Protocolized sedation effect on post-ICU posttraumatic stress disorder prevalence: A systematic review and network meta-analysis. J Crit Care. 30(6):1278-82. 10.1016/j.jcrc.2015.07.023.

Martin-Loeches I, Povoa P, RodrĂ­guez A, ..., Nseir S, TAVeM Study (2015). Incidence and prognosis of ventilator-associated tracheobronchitis (TAVeM): a multicentre, prospective, observational study. Lancet Respir Med. 3(11):859-68. 10.1016/s2213-2600(15)00326-4.

Prina E, Ranzani OT, Torres A (2015). Community-acquired pneumonia. Lancet. 386(9998):1097-108. 10.1016/s0140-6736(15)60733-4.

Sprung CL, Rusinova K, Ranzani OT (2015). Variability in forgoing life-sustaining treatments: reasons and recommendations. Intensive Care Med. 41(9):1679-81. 10.1007/s00134-015-3868-0.

Lazar Neto F, Ceccato A, Ranzani OT (2015). Corticosteroids in the Critically Ill Patient: Benefits and Risks for Hospital-acquired Pneumonia/Ventilator-associated Pneumonia. Clinical Pulmonary Medicine. 2015,22(5), e239-e240. 10.1097/CPM.0000000000000102.

Zampieri FG, Nassar AP Jr, Gusmao-Flores D, Taniguchi LU, Torres A, Ranzani OT (2015). Importance of a registered and structured protocol when conducting systematic reviews: comments about nebulized antibiotics for ventilator-associated pneumonia. Crit Care. 19(1):298. 10.1186/s13054-015-1020-8.

Jones C, Ranzani OT (2015). How should I structure my Post-ICU Clinic? From early goal rehabilitation to outpatient visits. Minerva Anestesiol. 45(2):81(8):832-4. PMID: 25479473.

Ranzani OT, Zampieri FG, Besen BA, Azevedo LC, Park M (2015). One-year survival and resource use after critical illness: impact of organ failure and residual organ dysfunction in a cohort study in Brazil. Crit Care. 19(1):269. 10.1186/s13054-015-0986-6.

Zampieri FG, Nassar AP Jr, Gusmao-Flores D, Taniguchi LU, Torres A, Ranzani OT (2015). Nebulized antibiotics for ventilator-associated pneumonia: a systematic review and meta-analysis. Crit Care. 19(1):150. 10.1186/s13054-015-0868-y.

Fumis RR, Ranzani OT, Faria PP, Schettino G (2015). Anxiety, depression, and satisfaction in close relatives of patients in an open visiting policy intensive care unit in Brazil. J Crit Care. 30(2):440.e1-6. 10.1016/j.jcrc.2014.11.022.

Ball J, Ranzani OT (2015). Hyperoxia following cardiac arrest. Intensive Care Med. 41(3):534-6. 10.1007/s00134-015-3660-1.

Li Bassi G, Fernandez-Barat L, Saucedo L, Ranzani OT, ..., Ferrer M, Torres A (2015). Endotracheal tube biofilm translocation in the lateral Trendelenburg position. Crit Care. 19(1):59. 10.1186/s13054-015-0785-0.

Prina E, Ranzani OT, Polverino E, Cillóniz C, Ferrer M, Fernandez L, Puig De La Bellacasa J, Menéndez R, Mensa J, Torres A (2015). Risk factors associated with potentially antibiotic-resistant pathogens in community-acquired pneumonia. Ann Am Thorac Soc. 12(2):153-60. 10.1513/annalsats.201407-305oc.

Casalino R, Tarasoutchi F, Spina G, Katz M, Bacelar A, Sampaio R, Ranzani OT, Pomerantzeff PM, Grinberg M (2015). EuroSCORE models in a cohort of patients with valvular heart disease and a high prevalence of rheumatic fever submitted to surgical procedures. PLoS One. 10(2):e0118357. 10.1371/journal.pone.0118357.

Fumis RR, Ranzani OT, Martins PS, Schettino G (2015). Emotional disorders in pairs of patients and their family members during and after ICU stay. PLoS One. 10(1):e0115332. 10.1371/journal.pone.0115332.

Ranzani OT, Simpson ES, Augusto TB, Cappi SB, Noritomi DT, Amil Critical Care Group (2014). Evaluation of a minimal sedation protocol using ICU sedative consumption as a monitoring tool: a quality improvement multicenter project. Crit Care. 18(5):580. 10.1186/s13054-014-0580-3.

Li Bassi G, Marti JD, Saucedo L, Ranzani OT, ..., Vila J, Torres A (2014). Gravity predominates over ventilatory pattern in the prevention of ventilator-associated pneumonia. Crit Care Med. 42(9):e620-7. 10.1097/ccm.0000000000000487.

Zampieri FG, Kellum JA, Park M, Ranzani OT, Barbeiro HV, De Souza HP, Da Cruz Neto LM, Da Silva FP (2014). Relationship between acid-base status and inflammation in the critically ill. Crit Care. 18(4):R154. 10.1186/cc13993.

Ranzani OT, Prina E, Torres A (2014). Nosocomial pneumonia in the intensive care unit: how should treatment failure be predicted?. Rev Bras Ter Intensiva. 26(3):208-11. 10.5935/0103-507x.20140032.

Li Bassi G, Rigol M, Marti JD, Ranzani OT, ..., Ramirez J, Torres A (2014). A novel porcine model of ventilator-associated pneumonia caused by oropharyngeal challenge with Pseudomonas aeruginosa. Anesthesiology. 120(5):1205-15. 10.1097/aln.0000000000000222.

Ranzani OT, Zampieri FG, Taniguchi LU, Forte DN, Azevedo LC, Park M (2014). The effects of discharge to an intermediate care unit after a critical illness: a 5-year cohort study. J Crit Care. 29(2):230-5. 10.1016/j.jcrc.2013.10.013.

Pirracchio R, Ranzani OT (2014). Recalibrating our prediction models in the ICU: time to move from the abacus to the computer. Intensive Care Med. 40(3):438-41. 10.1007/s00134-014-3231-x.

RodrĂ­guez A, PĂłvoa P, Nseir S, Salluh J, Curcio D, MartĂ­n-Loeches I, TAVeM Group Investigators (2014). Incidence and diagnosis of ventilator-associated tracheobronchitis in the intensive care unit: an international online survey. Crit Care. 18(1):R32. 10.1186/cc13725.

Noritomi DT, Ranzani OT, Monteiro MB, Ferreira EM, Santos SR, Leibel F, Machado FR (2014). Implementation of a multifaceted sepsis education program in an emerging country setting: clinical outcomes and cost-effectiveness in a long-term follow-up study. Intensive Care Med. 40(2):182-191. 10.1007/s00134-013-3131-5.

Zampieri FG, Ranzani OT, Sabatoski V, De Souza HP, Barbeiro H, Da Neto LM, Park M, Pinheiro Da Silva F (2014). An increase in mean platelet volume after admission is associated with higher mortality in critically ill patients. Ann Intensive Care. 4:20. 10.1186/s13613-014-0020-1.

Zampieri FG, Mendes PV, Ranzani OT, Taniguchi LU, Pontes Azevedo LC, Vieira Costa EL, Park M (2013). Extracorporeal membrane oxygenation for severe respiratory failure in adult patients: a systematic review and meta-analysis of current evidence. J Crit Care. 28(6):998-1005. 10.1016/j.jcrc.2013.07.047.

Capuzzo M, Ranzani OT (2013). How objective is the observed mortality following critical care?. Intensive Care Med. 39(11):2047-9. 10.1007/s00134-013-3079-5.

Ranzani OT, Monteiro MB, Ferreira EM, Santos SR, Machado FR, Noritomi DT, Grupo De Cuidados CrĂ­ticos Amil (2013). Reclassifying the spectrum of septic patients using lactate: severe sepsis, cryptic shock, vasoplegic shock and dysoxic shock. Rev Bras Ter Intensiva. 25(4):270-8. 10.5935/0103-507x.20130047.

Ranzani OT, Zampieri FG, Park M (2013). Highlighting the important effect of systemic lupus erythematosus on platelet count of critically ill patients. Intensive Care Med. 39(10):1882-3. 10.1007/s00134-013-3019-4.

Ranzani OT, Zampieri FG, Park M, Salluh JI (2013). Long-term mortality after critical care: what is the starting point?. Crit Care. 17(5):191. 10.1186/cc13024.

Esperatti M, Ferrer M, Giunta V, Ranzani OT, Saucedo LM, Li Bassi G, Blasi F, Rello J, Niederman MS, Torres A (2013). Validation of predictors of adverse outcomes in hospital-acquired pneumonia in the ICU. Crit Care Med. 41(9):2151-61. 10.1097/ccm.0b013e31828a674a.

Giunta V, Ferrer M, Esperatti M, Ranzani OT, Saucedo LM, Li Bassi G, Blasi F, Torres A (2013). ICU-acquired pneumonia with or without etiologic diagnosis: a comparison of outcomes. Crit Care Med. 41(9):2133-43. 10.1097/ccm.0b013e31828a453b.

Zampieri FG, Park M, Ranzani OT, Maciel AT, De Souza HP, Da Cruz Neto LM, Da Silva FP (2013). Anion gap corrected for albumin, phosphate and lactate is a good predictor of strong ion gap in critically ill patients: a nested cohort study. Rev Bras Ter Intensiva. 25(3):205-11. 10.5935/0103-507x.20130036.

Ranzani OT (2013). Blindness: perceptions under mechanical ventilation. Intensive Care Med. 39(6):1139. 10.1007/s00134-013-2892-1.

Zampieri FG, Ranzani OT, Morato PF, Campos PP, Caruso P (2013). Effect of intraoperative HES 6% 130/0.4 on the need for blood transfusion after major oncologic surgery: a propensity-matched analysis. Clinics (Sao Paulo). 68(4):501-9. 10.6061/clinics/2013(04)11.

Prina E, Ferrer M, Ranzani OT, ..., Cosentini R, Torres A (2013). Thrombocytosis is a marker of poor outcome in community-acquired pneumonia. Chest. 143(3):767-775. 10.1378/chest.12-1235.

MartĂ­ JD, Li Bassi G, Rigol M, Ranzani OT, ..., Kolobow T, Torres A (2013). Effects of manual rib cage compressions on expiratory flow and mucus clearance during mechanical ventilation. Crit Care Med. 41(3):850-6. 10.1097/ccm.0b013e3182711b52.

Li Bassi G, Ranzani OT, Marti JD, Giunta V, Luque N, Isetta V, Ferrer M, Farre R, Pimentel GL, Torres A (2013). An in vitro study to assess determinant features associated with fluid sealing in the design of endotracheal tube cuffs and exerted tracheal pressures. Crit Care Med. 41(2):518-26. 10.1097/ccm.0b013e31826a4804.

Li Bassi G, Ranzani OT, Torres A (2013). Systematic implementation of evidence-based guidelines in intensive care medicine: resistance to change is human nature. Crit Care Med. 41(1):329-31. 10.1097/ccm.0b013e318270e234.

Ranzani OT, Zampieri FG, Forte DN, Azevedo LC, Park M (2013). C-reactive protein/albumin ratio predicts 90-day mortality of septic patients. PLoS One. 8(3):e59321. 10.1371/journal.pone.0059321.

Ranzani OT, Prada LF, Zampieri FG, ..., Azevedo LC, Park M (2012). Failure to reduce C-reactive protein levels more than 25% in the last 24 hours before intensive care unit discharge predicts higher in-hospital mortality: a cohort study. J Crit Care. 27(5):525.e9-15. 10.1016/j.jcrc.2011.10.013.

Ranzani OT, Ferrer M, Esperatti M, Giunta V, Bassi GL, Carvalho CR, Torres A (2012). Association between systemic corticosteroids and outcomes of intensive care unit-acquired pneumonia. Crit Care Med. 40(9):2552-61. 10.1097/ccm.0b013e318259203d.

Li Bassi G, Ferrer M, Ranzani OT, Marti JD, Berra L, Fernandez L, Torres A (2012). Prevention of VAP: role of the artificial airway, body position and setting the ventilator. New Developments in Mechanical Ventilation (ERS Monograph). 2024. pp. 153–168. 10.1183/1025448x.10002511.

Ranzani OT, Battaini LC, Moraes CE, Prada LF, Pinaffi JV, Giannini FP, Shinjo SK, Azevedo LC, Park M (2011). Outcomes and organ dysfunctions of critically ill patients with systemic lupus erythematosus and other systemic rheumatic diseases. Braz J Med Biol Res. 44(11):1184-93. 10.1590/s0100-879x2011007500132.

Pego-Fernandes PM, Nascimbem MB, Ranzani OT, Shimoda MS, Monteiro R, Jatene FB (2011). Video-assisted thoracoscopy as an option in the surgical treatment of chylothorax after cardiac surgery in children. J Bras Pneumol. 37(1):28-35. 10.1590/s1806-37132011000100006.

Ranzani OT, Parra ER, De Morais Fernezlian S, Capelozzi VL (2007). Intraluminal plugs in idiopathic and secondary organizing pneumonia: repair or remodelling?. Histopathology. 51(5):622-30. 10.1111/j.1365-2559.2007.02845.x.

Pazetti R, Pego-Fernandes PM, Ranzani OT, Parra ER, Lorenzi-Filho G, Jatene FB (2007). Cyclosporin A reduces airway mucus secretion and mucociliary clearance in rats. Clinics (Sao Paulo). 62(3):345-52. 10.1590/s1807-59322007000300021.